Synedica vs Alluvi vs VLS Retatrutide UK — Complete Brand Comparison 2025
Three retatrutide brands dominate the UK market — Synedica, Alluvi and VLS. All three are independently COA verified, but there are meaningful differences in dose options, pricing and reputation. Here’s our honest comparison based on buyer feedback and independent testing data.
At a Glance — Brand Comparison
| Feature | Synedica | Alluvi | VLS |
|---|---|---|---|
| Doses available | 40mg only | 20mg and 40mg | 20mg and 40mg |
| UK price (40mg) | £299/month | £299/month | £265/month |
| COA verified | ✅ Janoshik | ✅ Janoshik | ✅ Janoshik |
| Purity | ≥98% | ≥98% | ≥98% |
| Popularity (UK) | ★★★★★ Most popular | ★★★★☆ Popular | ★★★☆☆ Growing |
| Best for | Established buyers at 8mg+ | New starters (20mg option) | Budget-conscious buyers |
Synedica Retatrutide — The UK Market Leader
Synedica is the UK’s most popular retatrutide brand — consistently our bestseller, with the strongest buyer reviews for product consistency and pen reliability. Synedica’s 40mg pen is the preferred choice for users who are established on their titration protocol (8mg+ weekly doses) and require the higher volume.
Buy: Synedica Retatrutide 40mg UK — £299 →
Pros: Market-leading reputation · Consistent COA scores · Reliable pen mechanism
Cons: 40mg only — no 20mg option for those preferring lower dose flexibility
Alluvi Retatrutide — Best for Flexible Titration
Alluvi’s key differentiator is the availability of both 20mg and 40mg pens. For users starting retatrutide for the first time or those who prefer titrating more slowly (staying at 2mg–6mg weekly doses for longer), the 20mg pen provides twice the number of doses per pen and allows finer control at lower dose levels.
Alluvi consistently scores well on independent COA testing and has strong buyer reviews, particularly among users who appreciate the lower dose flexibility.
Buy: Alluvi Retatrutide 40mg UK — £299 → · Alluvi Retatrutide 20mg UK — £249 →
Pros: 20mg option available · Good for slower titration · Strong COA scores
Cons: Slightly less name recognition than Synedica in the UK market
VLS Retatrutide — Best Value Brand
VLS offers the most competitive price in our retatrutide range at £265/month for the 40mg pen and £199/month for 20mg. VLS is a newer brand in the UK market but has established independent COA verification. For buyers who are price-sensitive or want to trial retatrutide before committing to higher-priced brands, VLS is a credible option.
Buy: VLS Retatrutide 40mg UK — £265 → · VLS Retatrutide 20mg UK — £199 →
Pros: Most competitive price · COA verified · 20mg option available
Cons: Less established UK buyer history than Synedica/Alluvi
Which Retatrutide Brand Should You Buy?
- First-time buyer: Alluvi 20mg (£249) — start slow, maximum flexibility
- Experienced buyer at 8mg+ weekly: Synedica 40mg (£299) — most trusted brand, maximum pen volume
- Price-conscious buyer: VLS 40mg (£265) — good value, COA verified
- Trying retatrutide for the first time on a budget: VLS 20mg (£199) — lowest entry cost
All three brands are independently COA verified at UK Peptides Store. Every order includes physician review, dosing protocol and 48hr UK delivery. Not sure? WhatsApp us for a personalised recommendation →